Roles of calcitonin gene-related peptide in the skin, and other physiological and pathophysiological functions

Roles of calcitonin gene-related peptide in the skin, and other physiological and pathophysiological functions

Blog Article

Skin immunity is regulated by many mediator molecules.One is the neuropeptide calcitonin gene-related ACCESSORIES peptide (CGRP).CGRP has roles in regulating the function of components of the immune system including T cells, B cells, dendritic cells (DCs), endothelial Outdoor Rocking Lounge Chair cells (ECs), and mast cells (MCs).Herein we discuss actions of CGRP in mediating inflammatory and vascular effects in various cutaneous models and disorders.